GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2251844 | 1 | rs2255440 | chr15:43830467 | ADAL | chr15:43622872-43646094:+ | -0.62 | -5.23 | 1.01E-6 | Tumor biomarkers |
| THYM | cis | rs2243480 | 1 | rs2257790 | chr7:65600450 | CCT6P1 | chr7:65216092-65228661:+ | 0.63 | 5.27 | 8.65E-7 | Diabetic kidney disease |
| THYM | cis | rs2251844 | 1 | rs2260160 | chr15:43895643 | ADAL | chr15:43622872-43646094:+ | -0.51 | -4.41 | 2.75E-5 | Tumor biomarkers |
| THYM | cis | rs2251844 | 1 | rs2260160 | chr15:43895643 | CATSPER2 | chr15:43922774-43959900:- | -0.57 | -4.35 | 3.47E-5 | Tumor biomarkers |
| THYM | cis | rs9815354 | 1 | rs2272006 | chr3:41997059 | ULK4 | chr3:41288091-42003660:- | -1.01 | -11.41 | 1.64E-19 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs2272007 | chr3:41996136 | ULK4 | chr3:41288091-42003660:- | -1.01 | -11.41 | 1.64E-19 | Diastolic blood pressure |
| THYM | cis | rs2273 | 1 | rs2273 | chr4:76889388 | NAAA | chr4:76831809-76862166:- | 0.46 | 4.92 | 3.56E-6 | Longevity |
| THYM | cis | rs2275426 | 1 | rs2275426 | chr1:46487552 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6.02 | 3.21E-8 | Body mass index |
| THYM | cis | rs9876781 | 1 | rs2279077 | chr3:48474249 | TREX1 | chr3:48501186-48509043:+ | -0.28 | -4.23 | 5.28E-5 | Longevity |
| THYM | cis | rs6585827 | 1 | rs2280141 | chr10:124193181 | PLEKHA1 | chr10:124134220-124191866:+ | -0.26 | -4.17 | 6.69E-5 | Height |
| THYM | cis | rs10416265 | 1 | rs2287679 | chr19:33600764 | GPATCH1 | chr19:33571786-33621318:+ | 0.37 | 4.33 | 3.69E-5 | Bone properties (heel) |
| THYM | cis | rs10416265 | 1 | rs2287680 | chr19:33608566 | GPATCH1 | chr19:33571786-33621318:+ | -0.37 | -4.33 | 3.69E-5 | Bone properties (heel) |
| THYM | cis | rs2288073 | 1 | rs2288073 | chr2:24413298 | LOC375190 | chr2:24299728-24397519:+ | 0.34 | 4.83 | 5.25E-6 | Venous thromboembolism (SNP x SNP interaction) |
| THYM | cis | rs2289681 | 1 | rs2289681 | chr17:42989088 | CCDC103 | chr17:42977154-42982758:+ | 0.63 | 4.8 | 5.99E-6 | Cognitive function |
| THYM | cis | rs2290416 | 1 | rs2290416 | chr8:144657600 | NAPRT1 | chr8:144656956-144660513:- | -0.73 | -4.76 | 6.88E-6 | Attention deficit hyperactivity disorder |